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The Link Between Adipose Tissue Renin-Angiotensin-Aldosterone System Signaling and Obesity-Associated Hypertension.
Schütten, Monica T J; Houben, Alfons J H M; de Leeuw, Peter W; Stehouwer, Coen D A.
Afiliação
  • Schütten MT; Department of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Houben AJ; Department of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • de Leeuw PW; Department of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Stehouwer CD; Department of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands cda.stehouwer@mumc.nl.
Physiology (Bethesda) ; 32(3): 197-209, 2017 05.
Article em En | MEDLINE | ID: mdl-28404736
ABSTRACT
Obese individuals frequently develop hypertension, which is for an important part attributable to renin-angiotensin-aldosterone system (RAAS) overactivity. This review summarizes preclinical and clinical evidence on the involvement of dysfunctional adipose tissue in RAAS activation and on the renal, central, and vascular mechanisms linking RAAS components to obesity-associated hypertension.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Renina-Angiotensina / Tecido Adiposo / Hipertensão / Obesidade Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Renina-Angiotensina / Tecido Adiposo / Hipertensão / Obesidade Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article