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Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions.
Sinha, Supriya; Li, Fuyang; Villarreal, Diana; Shim, Jae Hoon; Yoon, Suhyeon; Myung, Kyungjae; Shim, Eun Yong; Lee, Sang Eun.
Afiliação
  • Sinha S; Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States of America.
  • Li F; Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States of America.
  • Villarreal D; Children's Hospital of San Antonio, Baylor College of Medicine, San Antonio, TX, United States of America.
  • Shim JH; Korea Institute of Radiological & Medical Sciences (KIRAMS), 75 Nowon-ro, Nowon-gu, Seoul, Republic of Korea.
  • Yoon S; Department of Biological Science, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44818, Republic of Korea.
  • Myung K; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44818, Republic of Korea.
  • Shim EY; Department of Biological Science, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44818, Republic of Korea.
  • Lee SE; Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States of America.
PLoS Genet ; 13(4): e1006714, 2017 04.
Article em En | MEDLINE | ID: mdl-28419093
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Mutagênese / Proteínas de Saccharomyces cerevisiae / Reparo do DNA por Junção de Extremidades Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Mutagênese / Proteínas de Saccharomyces cerevisiae / Reparo do DNA por Junção de Extremidades Idioma: En Ano de publicação: 2017 Tipo de documento: Article