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Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene.
Fujihira, Haruhiko; Masahara-Negishi, Yuki; Tamura, Masaru; Huang, Chengcheng; Harada, Yoichiro; Wakana, Shigeharu; Takakura, Daisuke; Kawasaki, Nana; Taniguchi, Naoyuki; Kondoh, Gen; Yamashita, Tadashi; Funakoshi, Yoko; Suzuki, Tadashi.
Afiliação
  • Fujihira H; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
  • Masahara-Negishi Y; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
  • Tamura M; Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, BioResourse Center, RIKEN, Ibaraki, Japan.
  • Huang C; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
  • Harada Y; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
  • Wakana S; Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, BioResourse Center, RIKEN, Ibaraki, Japan.
  • Takakura D; Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan.
  • Kawasaki N; Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan.
  • Taniguchi N; Disease Glycomics Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
  • Kondoh G; Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Yamashita T; Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
  • Funakoshi Y; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
  • Suzuki T; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan.
PLoS Genet ; 13(4): e1006696, 2017 04.
Article em En | MEDLINE | ID: mdl-28426790
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Manosil-Glicoproteína Endo-beta-N-Acetilglucosaminidase / Peptídeo-N4-(N-acetil-beta-glucosaminil) Asparagina Amidase / Doenças Genéticas Inatas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Manosil-Glicoproteína Endo-beta-N-Acetilglucosaminidase / Peptídeo-N4-(N-acetil-beta-glucosaminil) Asparagina Amidase / Doenças Genéticas Inatas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article