Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry.

Gregorich, Zachery R; Cai, Wenxuan; Lin, Ziqing; Chen, Albert J; Peng, Ying; Kohmoto, Takushi; Ge, Ying

Gregorich, Zachery R; Cai, Wenxuan; Lin, Ziqing; Chen, Albert J; Peng, Ying; Kohmoto, Takushi; Ge, Ying.

Afiliação

Gregorich ZR; Molecular and Cellular Pharmacology Training Program, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Cai W; Molecular and Cellular Pharmacology Training Program, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Lin Z; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Chen AJ; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Peng Y; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Kohmoto T; Department of Surgery, University of Wisconsin-Madison, Madison, WI 53705, USA.
Ge Y; Molecular and Cellular Pharmacology Training Program, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA; Human Proteomics Program, University of Wisconsin-Madison, Madison, WI 53705, USA; Depa

J Mol Cell Cardiol ; 107: 13-21, 2017 06.

Article em En | MEDLINE | ID: mdl-28427997

Assuntos

Átrios do Coração/metabolismo; Miocárdio/metabolismo; Cadeias Leves de Miosina/genética; Isoformas de Proteínas/genética; Animais; Ventrículos do Coração/metabolismo; Humanos; Miocárdio/patologia; Cadeias Leves de Miosina/metabolismo; Fosforilação; Isoformas de Proteínas/metabolismo; Processamento de Proteína Pós-Traducional/genética; Sarcômeros/metabolismo; Suínos

Palavras-chave

Acetylation; Methylation; Myosin light chain; Phosphorylation; Post-translational modification; Top-down mass spectrometry

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cadeias Leves de Miosina / Isoformas de Proteínas / Átrios do Coração / Miocárdio Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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