Chiral Fidelity in the Diastereoselective and Enantiospecific Synthesis of Indenes from Axially Chiral Benzylidene Cyclanes.
Chemistry
; 23(35): 8375-8379, 2017 Jun 22.
Article
em En
| MEDLINE
| ID: mdl-28436112
ABSTRACT
Enantioenriched indenes were reached through a chirality conversion strategy using original axially chiral benzylidene cyclanes. Good to high remote diastereocontrol and excellent enantiocontrol were observed in this cascade involving copper-catalyzed homologation of terminal alkynes, in situ allenoate formation and Alder-ene cyclization.
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MEDLINE
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En
Ano de publicação:
2017
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Article