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A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.
Karlgren, Maria; Simoff, Ivailo; Backlund, Maria; Wegler, Christine; Keiser, Markus; Handin, Niklas; Müller, Janett; Lundquist, Patrik; Jareborg, Anne-Christine; Oswald, Stefan; Artursson, Per.
Afiliação
  • Karlgren M; Department of Pharmacy, Uppsala University, Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform, Science for Life Laboratory, Uppsala, Sweden. Electronic address: maria.karlgren@farmaci.uu.se.
  • Simoff I; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Backlund M; Department of Pharmacy, Uppsala University, Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform, Science for Life Laboratory, Uppsala, Sweden.
  • Wegler C; Department of Pharmacy, Uppsala University, Uppsala, Sweden; Cardiovascular Metabolic Diseases DMPK, AstraZeneca R&D, Mölndal, Sweden.
  • Keiser M; Department of Clinical Pharmacology, Center of Drug Absorption and Transport, University Medicine of Greifswald, Greifswald, Germany.
  • Handin N; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Müller J; Department of Clinical Pharmacology, Center of Drug Absorption and Transport, University Medicine of Greifswald, Greifswald, Germany.
  • Lundquist P; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Jareborg AC; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Oswald S; Department of Clinical Pharmacology, Center of Drug Absorption and Transport, University Medicine of Greifswald, Greifswald, Germany.
  • Artursson P; Department of Pharmacy, Uppsala University, Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform, Science for Life Laboratory, Uppsala, Sweden.
J Pharm Sci ; 106(9): 2909-2913, 2017 09.
Article em En | MEDLINE | ID: mdl-28450237
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article