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Hispidin induces autophagic and necrotic death in SGC-7901 gastric cancer cells through lysosomal membrane permeabilization by inhibiting tubulin polymerization.
Lv, Long-Xian; Zhou, Zhen-Xing; Zhou, Zhan; Zhang, Li-Jiang; Yan, Ren; Zhao, Zhao; Yang, Li-Ya; Bian, Xiao-Yuan; Jiang, Hui-Yong; Li, Yu-Dong; Sun, Yi-Sheng; Xu, Qin-Qin; Hu, Gui-Li; Guan, Wen-Jun; Li, Yong-Quan.
Afiliação
  • Lv LX; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Zhou ZX; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China.
  • Zhou Z; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Zhang LJ; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Yan R; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Zhao Z; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China.
  • Yang LY; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Bian XY; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China.
  • Jiang HY; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China.
  • Li YD; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China.
  • Sun YS; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Xu QQ; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Hu GL; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
  • Guan WJ; Department of Basic Medicine, College of Medicine, Zhejiang University, 310058 Hangzhou, China.
  • Li YQ; Institute of Pharmaceutical Biotechnology and College of Pharmaceutical Sciences, Zhejiang University, 310058 Hangzhou, China.
Oncotarget ; 8(16): 26992-27006, 2017 Apr 18.
Article em En | MEDLINE | ID: mdl-28460485
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Autofagia / Tubulina (Proteína) / Multimerização Proteica / Membranas Intracelulares / Lisossomos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Autofagia / Tubulina (Proteína) / Multimerização Proteica / Membranas Intracelulares / Lisossomos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article