Comparison of Visual Outcomes in Coats' Disease: A 20-Year Experience.
Ophthalmology
; 124(9): 1368-1376, 2017 09.
Article
em En
| MEDLINE
| ID: mdl-28461016
ABSTRACT
PURPOSE:
To report differences in visual acuities among patients with Coats' disease who sought treatment at a tertiary care university-based practice.DESIGN:
Single-center retrospective cohort study.PARTICIPANTS:
Patients with Coats' disease diagnosed clinically, angiographically, or both from 1995 through 2015.METHODS:
Patients were divided into 2 groups based on date of presentation decade 1 (1995-2005) and decade 2 (2006-2015). MAIN OUTCOMEMEASURES:
Visual acuity (VA).RESULTS:
Thirty-nine eyes of 39 patients were included with 19 eyes presenting in decade 1 and 20 eyes presenting in decade 2. Three patients demonstrated bilateral disease, but only the worse eye was included for analysis. Forty-seven percent of eyes in decade 1 demonstrated advanced stages of disease (stage 3B or worse) compared with 20% of eyes in decade 2. There was a trend for the mean initial presenting VA (±standard deviation) for decade 1 eyes to be worse (2.05±1.29 logarithm of the minimum angle of resolution [logMAR]) than for decade 2 eyes (1.45±0.99 logMAR; P = 0.1). From initial to final follow-up visit, mean VA also worsened for decade 1 eyes (P = 0.03), but remained stable for decade 2 eyes (P = 1.0). At the end of follow-up, there was a trend for mean VA for decade 1 eyes (2.28±1.17 logMAR) to be worse than for decade 2 eyes (1.60±1.15 logMAR; P = 0.07). Eight eyes were observed initially in decade 1 compared with 1 eye in decade 2, and only 1 of the observed eyes (in decade 2) developed painful glaucoma requiring enucleation. Decade 2 eyes had a higher average number of procedures per eye (6.5±4.9) compared with decade 1 eyes (1.4±1.7; P < 0.001).CONCLUSIONS:
The earlier presentation of disease in decade 2 suggests improvements in disease detection over time. Furthermore, there was a trend for eyes to have better final VA in this decade. This is due to a combination of factors, including earlier presentation of disease, fewer eyes being observed without treatment, and eyes, when treated, receiving a higher number of procedures.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Acuidade Visual
/
Telangiectasia Retiniana
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
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Incidence_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article