Examination of PHOX2B in adult neuroendocrine neoplasms reveals relatively frequent expression in phaeochromocytomas and paragangliomas.

Lee, John P; Hung, Yin P; O'Dorisio, Thomas M; Howe, James R; Hornick, Jason L; Bellizzi, Andrew M

Lee, John P; Hung, Yin P; O'Dorisio, Thomas M; Howe, James R; Hornick, Jason L; Bellizzi, Andrew M.

Afiliação

Lee JP; Department of Pathology, University of Iowa Hospitals and Clinics and Carver College of Medicine, Iowa City, IA, USA.
Hung YP; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
O'Dorisio TM; Department of Internal Medicine, University of Iowa Hospitals and Clinics and Carver College of Medicine, Iowa City, IA, USA.
Howe JR; University of Iowa Neuroendocrine Tumor Specialized Program of Research Excellence (SPORE), Iowa City, IA, USA.
Hornick JL; University of Iowa Neuroendocrine Tumor Specialized Program of Research Excellence (SPORE), Iowa City, IA, USA.
Bellizzi AM; Department of Surgery, University of Iowa Hospitals and Clinics and Carver College of Medicine, Iowa City, IA, USA.

Histopathology ; 71(4): 503-510, 2017 Oct.

Article em En | MEDLINE | ID: mdl-28464318

Assuntos

Neoplasias das Glândulas Suprarrenais/metabolismo; Proteínas de Homeodomínio/metabolismo; Neuroblastoma/patologia; Tumores Neuroendócrinos/metabolismo; Paraganglioma/metabolismo; Feocromocitoma/metabolismo; Fatores de Transcrição/metabolismo; Neoplasias das Glândulas Suprarrenais/patologia; Adulto; Estudos de Coortes; Proteínas de Homeodomínio/genética; Humanos; Neuroblastoma/metabolismo; Tumores Neuroendócrinos/patologia; Paraganglioma/patologia; Feocromocitoma/patologia; Análise Serial de Tecidos; Fatores de Transcrição/genética

Palavras-chave

PHOX2B; differential diagnosis; immunohistochemistry; neuroendocrine; paraganglioma; phaeochromocytoma; transcription factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paraganglioma / Feocromocitoma / Fatores de Transcrição / Tumores Neuroendócrinos / Neoplasias das Glândulas Suprarrenais / Proteínas de Homeodomínio / Neuroblastoma Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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