Graphical Modeling Meets Systems Pharmacology.
Gene Regul Syst Bio
; 11: 1177625017691937, 2017.
Article
em En
| MEDLINE
| ID: mdl-28469411
ABSTRACT
A main source of failures in systems projects (including systems pharmacology) is poor communication level and different expectations among the stakeholders. A common and not ambiguous language that is naturally comprehensible by all the involved players is a boost to success. We present bStyle, a modeling tool that adopts a graphical language close enough to cartoons to be a common media to exchange ideas and data and that it is at the same time formal enough to enable modeling, analysis, and dynamic simulations of a system. Data analysis and simulation integrated in the same application are fundamental to understand the mechanisms of actions of drugs a core aspect of systems pharmacology.
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MEDLINE
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En
Ano de publicação:
2017
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Article