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SYD985, a novel duocarmycin-based HER2-targeting antibody-drug conjugate, shows promising antitumor activity in epithelial ovarian carcinoma with HER2/Neu expression.
Menderes, Gulden; Bonazzoli, Elena; Bellone, Stefania; Black, Jonathan; Altwerger, Gary; Masserdotti, Alice; Pettinella, Francesca; Zammataro, Luca; Buza, Natalia; Hui, Pei; Wong, Serena; Litkouhi, Babak; Ratner, Elena; Silasi, Dan-Arin; Huang, Gloria S; Azodi, Masoud; Schwartz, Peter E; Santin, Alessandro D.
Afiliação
  • Menderes G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Bonazzoli E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Bellone S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Black J; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Altwerger G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Masserdotti A; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Pettinella F; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Zammataro L; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Buza N; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Hui P; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Wong S; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Litkouhi B; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Ratner E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Silasi DA; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Huang GS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Azodi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Schwartz PE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA. Electronic address: alessandro.santin@yale.edu.
Gynecol Oncol ; 146(1): 179-186, 2017 07.
Article em En | MEDLINE | ID: mdl-28473206
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Imunotoxinas / Neoplasias Epiteliais e Glandulares / Receptor ErbB-2 / Indóis Tipo de estudo: Clinical_trials Limite: Adult / Aged / Animals / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Imunotoxinas / Neoplasias Epiteliais e Glandulares / Receptor ErbB-2 / Indóis Tipo de estudo: Clinical_trials Limite: Adult / Aged / Animals / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article