Spontaneously Reported Symptoms by Informants Are Associated with Clinical Severity in Dementia Help-Seekers.
J Am Geriatr Soc
; 65(9): 1946-1952, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28481449
ABSTRACT
OBJECTIVES:
To investigate the predictive value of symptoms of dementia that the person or an informant noticed spontaneously in determining the clinical severity of dementia.DESIGN:
Cross-sectional.SETTING:
Community-based open-referral dementia assessment service in Hong Kong between 2005 and 2013.PARTICIPANTS:
Help-seekers for dementia assessment service and their informants (N = 965 dyads). MEASUREMENTS Participants underwent a clinical dementia interview based on the Clinical Dementia Rating. Spontaneous complaints that the person and the informant made that had prompted their help-seeking of groups with interview results suggestive of no impairment, mild cognitive impairment, and dementia were compared. Logistic regression was used to evaluate the predictive value of spontaneous complaints for clinical severity. Independent raters blinded to clinical results coded spontaneously reported symptoms into theoretical themes memory, executive function, language, time and place orientation, neuropsychiatric, mood, and avolition.RESULTS:
Memory problems were the most frequently reported complaints for participants (87.7%) and their informants (95.5%), followed by self-reported language (33.0%) and informant-reported orientation (33.0%) difficulties. Informant-reported but not self-reported symptoms predicted clinical severity. Compared with the persons themselves, informants reported more pervasive symptoms corresponding to clinical severity. Persons with dementia self-reported fewer types of symptoms than their healthy or mildly impaired counterparts. Spontaneously reported language and orientation symptoms by the informant distinguished persons with mild or worse dementia (P < .001, Nagelkerke coefficient of determination = 29.7%, percentage correct 85.6%).CONCLUSION:
The type and pervasiveness of symptoms spontaneously that informants reported predicted clinical severity. This may provide a quick reference for triage.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Transtornos Cognitivos
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Demência
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Autorrelato
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Qualitative_research
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article