The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in mice.

Zhong, Jianjun; Jiang, Li; Huang, Zhijian; Zhang, Hongrong; Cheng, Chongjie; Liu, Han; He, Junchi; Wu, Jingchuan; Darwazeh, Rami; Wu, Yue; Sun, Xiaochuan

Zhong, Jianjun; Jiang, Li; Huang, Zhijian; Zhang, Hongrong; Cheng, Chongjie; Liu, Han; He, Junchi; Wu, Jingchuan; Darwazeh, Rami; Wu, Yue; Sun, Xiaochuan.

Afiliação

Zhong J; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Jiang L; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China. Electronic address: 156313147@qq.com.
Huang Z; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Zhang H; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Cheng C; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Liu H; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
He J; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Wu J; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Darwazeh R; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Wu Y; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China.
Sun X; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, China. Electronic address: sunxch1445@qq.com.

Brain Behav Immun ; 65: 183-194, 2017 Oct.

Article em En | MEDLINE | ID: mdl-28483659

Assuntos

Lesões Encefálicas Traumáticas/terapia; RNA Longo não Codificante/metabolismo; RNA Longo não Codificante/uso terapêutico; Animais; Apoptose/efeitos dos fármacos; Bexaroteno; Lesões Encefálicas Traumáticas/genética; Lesões Encefálicas Traumáticas/metabolismo; Inflamação/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Neurogênese/efeitos dos fármacos; Neurônios/metabolismo; Fármacos Neuroprotetores/farmacologia; RNA Longo não Codificante/genética; Tetra-Hidronaftalenos/farmacologia; Tetra-Hidronaftalenos/uso terapêutico; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Bexarotene; Neat1; Pidd1; RXR; TBI; lncRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Longo não Codificante / Lesões Encefálicas Traumáticas Tipo de estudo: Guideline / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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