Clinical Significance of Isolated Atypical Transient Symptoms in a Cohort With Transient Ischemic Attack.
Stroke
; 48(6): 1495-1500, 2017 06.
Article
em En
| MEDLINE
| ID: mdl-28487336
ABSTRACT
BACKGROUND AND PURPOSE:
Contrary to typical transient symptoms (TS), atypical TS, such as partial sensory deficit, dysarthria, vertigo/unsteadiness, unusual cortical visual deficit, and diplopia, are not usually classified as symptoms of transient ischemic attack when they occur in isolation, and their clinical relevance is frequently denied.METHODS:
Consecutive patients with recent TS admitted in our transient ischemic attack clinic (2003-2008) had systematic brain, arterial, and cardiac investigations. We compared the prevalence of recent infarction on brain imaging, major investigational findings (symptomatic intracranial or extracranial atherosclerotic stenosis ≥50%, cervical arterial dissection, and major source of cardiac embolism), and 1-year risk of major vascular events in patients with isolated typical or atypical TS and nonisolated TS, after exclusion of the main differential diagnoses.RESULTS:
Among 1850 patients with possible or definite ischemic diagnoses, 798 (43.1%) had isolated TS 621 (33.6%) typical and 177 (9.6%) atypical. Acute infarction on brain imaging was similar in patients with isolated atypical and typical TS but less frequent than in patients with nonisolated TS, observed in 10.0%, 11.5%, and 15.3%, respectively (P<0.0001). Major investigational findings were found in 18.1%, 26.4%, and 26.3%, respectively (P=0.06). One-year risk of a major vascular events was not significantly different in the 3 groups.CONCLUSIONS:
Transient ischemic attack diagnosis should be considered and investigated in patients with isolated atypical TS.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Infarto Cerebral
/
Ataque Isquêmico Transitório
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Incidence_studies
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Observational_studies
/
Risk_factors_studies
Limite:
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article