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TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.
Wang, Bin; Jie, Zuliang; Joo, Donghyun; Ordureau, Alban; Liu, Pengda; Gan, Wenjian; Guo, Jianping; Zhang, Jinfang; North, Brian J; Dai, Xiangpeng; Cheng, Xuhong; Bian, Xiuwu; Zhang, Lingqiang; Harper, J Wade; Sun, Shao-Cong; Wei, Wenyi.
Afiliação
  • Wang B; Department of Gastroenterology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China.
  • Jie Z; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Joo D; Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, Texas 77030, USA.
  • Ordureau A; Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, Texas 77030, USA.
  • Liu P; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Gan W; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Guo J; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Zhang J; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • North BJ; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Dai X; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Cheng X; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Bian X; Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, Texas 77030, USA.
  • Zhang L; Institute of Pathology and Southwest Cancer Center and Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Harper JW; State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Collaborative Innovation Center for Cancer Medicine, Beijing 100850, China.
  • Sun SC; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Wei W; Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, Texas 77030, USA.
Nature ; 545(7654): 365-369, 2017 05 18.
Article em En | MEDLINE | ID: mdl-28489822

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Transdução de Sinais / Ubiquitina / Complexos Multiproteicos / Fator 2 Associado a Receptor de TNF / Ubiquitinação / Serina-Treonina Quinases TOR / Carcinogênese Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Transdução de Sinais / Ubiquitina / Complexos Multiproteicos / Fator 2 Associado a Receptor de TNF / Ubiquitinação / Serina-Treonina Quinases TOR / Carcinogênese Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article