The Expanding Prominence of Toxic Leukoencephalopathy.
J Neuropsychiatry Clin Neurosci
; 29(4): 308-318, 2017.
Article
em En
| MEDLINE
| ID: mdl-28506192
ABSTRACT
Toxic leukoencephalopathy (TL) is a disorder of brain white matter caused by exposure to leukotoxic agents. Magnetic resonance imaging (MRI) can readily identify this syndrome, and, together with diffusion tensor imaging, MRI continues to offer important insights into its nature. Since the first formal description of TL in 2001, many new leukotoxic disorders have been recognized, and the range of leukotoxins has expanded to include more therapeutic drugs, drugs of abuse, and environmental insults. While the understanding of pathophysiology remains incomplete, TL is increasingly common in clinical practice, and the potential long-term cognitive sequelae of toxic white matter injury merit attention.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndromes Neurotóxicas
/
Leucoencefalopatias
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article