Light chain Fanconi syndrome in a patient with acute myeloid leukemia and monoclonal gammopathy of undetermined significance.
CEN Case Rep
; 5(2): 238-241, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-28508985
ABSTRACT
Proximal tubules are a target for paraproteinemic diseases. Cast nephropathy, light chain deposition diseases, and amyloidosis are frequently encountered in patients with multiple myeloma. Rarely, a subset of patients develop light chain Fanconi syndrome (LCFS). LCFS has been reported with multiple myeloma, monoclonal gammopathy of renal significance (MGRS), chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia and diffuse large B-cell lymphoma. No cases have been described with other hematologic malignancies. We report the first case of lambda LCFS in a patient with both acute myeloid leukemia (AML) and monoclonal gammopathy of undetermined significance (MGUS).
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2016
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Article