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Identification of GalNAc-Conjugated Antisense Oligonucleotide Metabolites Using an Untargeted and Generic Approach Based on High Resolution Mass Spectrometry.
Husser, Christophe; Brink, Andreas; Zell, Manfred; Müller, Martina B; Koller, Erich; Schadt, Simone.
Afiliação
  • Husser C; Roche Pharma Research and Early Development, Roche Innovation Center Basel , Grenzacherstr. 124, CH-4070 Basel, Switzerland.
  • Brink A; Roche Pharma Research and Early Development, Roche Innovation Center Basel , Grenzacherstr. 124, CH-4070 Basel, Switzerland.
  • Zell M; Roche Pharma Research and Early Development, Roche Innovation Center Basel , Grenzacherstr. 124, CH-4070 Basel, Switzerland.
  • Müller MB; Roche Pharma Research and Early Development, Roche Innovation Center Basel , Grenzacherstr. 124, CH-4070 Basel, Switzerland.
  • Koller E; Roche Pharma Research and Early Development, Roche Innovation Center Basel , Grenzacherstr. 124, CH-4070 Basel, Switzerland.
  • Schadt S; Roche Pharma Research and Early Development, Roche Innovation Center Basel , Grenzacherstr. 124, CH-4070 Basel, Switzerland.
Anal Chem ; 89(12): 6821-6826, 2017 06 20.
Article em En | MEDLINE | ID: mdl-28520401
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilgalactosamina / Espectrometria de Massas / Cromatografia Líquida de Alta Pressão / Oligonucleotídeos Antissenso Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilgalactosamina / Espectrometria de Massas / Cromatografia Líquida de Alta Pressão / Oligonucleotídeos Antissenso Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article