chimeraviz: a tool for visualizing chimeric RNA.
Bioinformatics
; 33(18): 2954-2956, 2017 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-28525538
ABSTRACT
SUMMARY:
Advances in high-throughput RNA sequencing have enabled more efficient detection of fusion transcripts, but the technology and associated software used for fusion detection from sequencing data often yield a high false discovery rate. Good prioritization of the results is important, and this can be helped by a visualization framework that automatically integrates RNA data with known genomic features. Here we present chimeraviz , a Bioconductor package that automates the creation of chimeric RNA visualizations. The package supports input from nine different fusion-finder tools deFuse, EricScript, InFusion, JAFFA, FusionCatcher, FusionMap, PRADA, SOAPfuse and STAR-FUSION. AVAILABILITY AND IMPLEMENTATION chimeraviz is an R package available via Bioconductor ( https//bioconductor.org/packages/release/bioc/html/chimeraviz.html ) under Artistic-2.0. Source code and support is available at GitHub ( https//github.com/stianlagstad/chimeraviz ). CONTACT rolf.i.skotheim@rr-research.no. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Software
/
Splicing de RNA
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Análise de Sequência de RNA
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Sequenciamento de Nucleotídeos em Larga Escala
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article