chimeraviz: a tool for visualizing chimeric RNA.

ABSTRACT

SUMMARY: Advances in high-throughput RNA sequencing have enabled more efficient detection of fusion transcripts, but the technology and associated software used for fusion detection from sequencing data often yield a high false discovery rate. Good prioritization of the results is important, and this can be helped by a visualization framework that automatically integrates RNA data with known genomic features. Here we present chimeraviz , a Bioconductor package that automates the creation of chimeric RNA visualizations. The package supports input from nine different fusion-finder tools deFuse, EricScript, InFusion, JAFFA, FusionCatcher, FusionMap, PRADA, SOAPfuse and STAR-FUSION. AVAILABILITY AND IMPLEMENTATION chimeraviz is an R package available via Bioconductor ( https//bioconductor.org/packages/release/bioc/html/chimeraviz.html ) under Artistic-2.0. Source code and support is available at GitHub ( https//github.com/stianlagstad/chimeraviz ). CONTACT rolf.i.skotheim@rr-research.no. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.