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Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia.
Mori, Mattia; Tottone, Luca; Quaglio, Deborah; Zhdanovskaya, Nadezda; Ingallina, Cinzia; Fusto, Marisa; Ghirga, Francesca; Peruzzi, Giovanna; Crestoni, Maria Elisa; Simeoni, Fabrizio; Giulimondi, Francesca; Talora, Claudio; Botta, Bruno; Screpanti, Isabella; Palermo, Rocco.
Afiliação
  • Mori M; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, 00161, Italy.
  • Tottone L; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy.
  • Quaglio D; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, 00185, Italy.
  • Zhdanovskaya N; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy.
  • Ingallina C; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, 00185, Italy.
  • Fusto M; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy.
  • Ghirga F; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, 00161, Italy.
  • Peruzzi G; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, 00161, Italy.
  • Crestoni ME; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, 00185, Italy.
  • Simeoni F; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy.
  • Giulimondi F; Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, UK.
  • Talora C; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy.
  • Botta B; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy.
  • Screpanti I; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, 00185, Italy. bruno.botta@uniroma1.it.
  • Palermo R; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy. isabella.screpanti@uniroma1.it.
Sci Rep ; 7(1): 2213, 2017 05 19.
Article em En | MEDLINE | ID: mdl-28526832

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Chalconas / Receptores Notch / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Chalconas / Receptores Notch / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article