Enzymatic biosynthesis of novel neobavaisoflavone glucosides via Bacillus UDP-glycosyltransferase.

Ma, Tao; Dai, Yi-Qun; Li, Nan; Huo, Qiang; Li, Hong-Mei; Zhang, Yu-Xin; Piao, Zheng-Hao; Wu, Cheng-Zhu

Ma, Tao; Dai, Yi-Qun; Li, Nan; Huo, Qiang; Li, Hong-Mei; Zhang, Yu-Xin; Piao, Zheng-Hao; Wu, Cheng-Zhu.

Afiliação

Ma T; School of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Dai YQ; School of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Li N; School of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Huo Q; School of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Li HM; School of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Zhang YX; Department of Biochemistry, Bengbu Medical College, Bengbu 233030, China.
Piao ZH; Department of Basic Medical Science, School of Medicine, Hangzhou Normal University, Hangzhou 321004, China.
Wu CZ; School of Pharmacy, Bengbu Medical College, Bengbu 233030, China. Electronic address: wuchengzhu0611@foxmail.com.

Chin J Nat Med ; 15(4): 281-287, 2017 Apr.

Article em En | MEDLINE | ID: mdl-28527513

Assuntos

Glucosídeos/biossíntese; Glicosiltransferases/metabolismo; Isoflavonas/biossíntese; Antineoplásicos/metabolismo; Antineoplásicos/farmacologia; Bacillus/enzimologia; Linhagem Celular Tumoral; Colorimetria; Ensaios de Seleção de Medicamentos Antitumorais; Glucosídeos/química; Humanos; Isoflavonas/química; Estrutura Molecular; Solubilidade

Palavras-chave

Cytotoxicity; Glycosylation; Neobavaisoflavone; UDP-glycosyltransferase; Water-solubility

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicosiltransferases / Glucosídeos / Isoflavonas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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