Isolation, Purification, and Characterization of Five Active Diketopiperazine Derivatives from Endophytic <i>Streptomyces</i> SUK 25 with Antimicrobial and Cytotoxic Activities.

Alshaibani, Muhanna; Zin, Noraziah Mohamad; Jalil, Juriyati; Sidik, Nik; Ahmad, Siti Junaidah; Kamal, Nurkhalida; Edrada-Ebel, Ruangelie

Isolation, Purification, and Characterization of Five Active Diketopiperazine Derivatives from Endophytic Streptomyces SUK 25 with Antimicrobial and Cytotoxic Activities.

Alshaibani, Muhanna; Zin, Noraziah Mohamad; Jalil, Juriyati; Sidik, Nik; Ahmad, Siti Junaidah; Kamal, Nurkhalida; Edrada-Ebel, Ruangelie.

Afiliação

Alshaibani M; Programme of Biomedical Science, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
Zin NM; Programme of Biomedical Science, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
Jalil J; Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
Sidik N; Faculty of Ago-based Industry, Universiti Malaysia Kelantan, 17600 Jeli, Kelantan, Malaysia.
Ahmad SJ; Programme of Biomedical Science, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
Kamal N; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, Scotland.
Edrada-Ebel R; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Cyberjaya University College of Medical Sciences, 63000 Cyberjaya, Selangor Malaysia.

J Microbiol Biotechnol ; 27(7): 1249-1256, 2017 07 28.

Article em En | MEDLINE | ID: mdl-28535606

Assuntos

Antibacterianos/farmacologia; Bactérias/efeitos dos fármacos; Citotoxinas/farmacologia; Dicetopiperazinas/isolamento & purificação; Dicetopiperazinas/farmacologia; Streptomyces/química; Cromatografia Líquida de Alta Pressão; Citotoxinas/química; Citotoxinas/isolamento & purificação; Dicetopiperazinas/química; Farmacorresistência Bacteriana Múltipla; Endófitos/química; Humanos; Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos; Peptídeos Cíclicos/química; Peptídeos Cíclicos/isolamento & purificação; Peptídeos Cíclicos/farmacologia; Metabolismo Secundário; Staphylococcus aureus/efeitos dos fármacos

Palavras-chave

Cytotoxicity; Enterococcus raffinosus; HepaRG; MRSA; Streptomyces SUK 25; diketopiperazines

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptomyces / Bactérias / Citotoxinas / Dicetopiperazinas / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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