Development and validation of a novel quantification approach for gradient elution reversed phase high-performance liquid chromatography coupled to tandem ICP-mass spectrometry (RP-HPLC-ICP-MS/MS) and its application to diclofenac and its related compounds.

Klencsár, Balázs; Balcaen, Lieve; Cuyckens, Filip; Lynen, Frédéric; Vanhaecke, Frank

Klencsár, Balázs; Balcaen, Lieve; Cuyckens, Filip; Lynen, Frédéric; Vanhaecke, Frank.

Afiliação

Klencsár B; Ghent University, Department of Analytical Chemistry, Campus Sterre, Krijgslaan 281-S12, 9000 Ghent, Belgium.
Balcaen L; Ghent University, Department of Analytical Chemistry, Campus Sterre, Krijgslaan 281-S12, 9000 Ghent, Belgium.
Cuyckens F; Janssen R&D, Pharmacokinetics, Dynamics & Metabolism, Turnhoutseweg 30, 2340 Beerse, Belgium.
Lynen F; Ghent University, Department of Organic and Macromolecular Chemistry, Campus Sterre, Krijgslaan 281-S4-bis, 9000 Ghent, Belgium.
Vanhaecke F; Ghent University, Department of Analytical Chemistry, Campus Sterre, Krijgslaan 281-S12, 9000 Ghent, Belgium. Electronic address: frank.vanhaecke@ugent.be.

Anal Chim Acta ; 974: 43-53, 2017 Jun 29.

Article em En | MEDLINE | ID: mdl-28535880