How Should We Treat HAP/VAP Caused by Carbapenemase-Producing Enterobacteriaceae?
Semin Respir Crit Care Med
; 38(3): 301-310, 2017 06.
Article
em En
| MEDLINE
| ID: mdl-28578554
ABSTRACT
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) represent a common problem in hospital setting worldwide. Infections caused by carbapenem-resistant Enterobacteriaceae (CRE) are an emergent problem due to the lack of therapeutic options available, leading to significant increases in morbidity and mortality. CRE have frequently been reported both in HAP/VAP, but limited data regarding the optimal treatment strategy in this setting are available. This review focuses on the current epidemiology of CRE, with a specific focus on HAP/VAP. Moreover, we will suggest a possible strategy for the empiric and targeted treatment of HAP and VAP in which the involvement of CRE is suspected or is confirmed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Enterobacteriaceae
/
Pneumonia Associada à Ventilação Mecânica
/
Antibacterianos
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article