Prevention of IcaA regulated poly N-acetyl glucosamine formation in Staphylococcus aureus biofilm through new-drug like inhibitors: In silico approach and MD simulation study.

Gupta, Ayushi; Mishra, Swechha; Singh, Sangeeta; Mishra, Sonali

Gupta, Ayushi; Mishra, Swechha; Singh, Sangeeta; Mishra, Sonali.

Afiliação

Gupta A; Applied Science Department, Indian Institute of Information Technology, Allahabad 211012, Uttar Pradesh, India.
Mishra S; Applied Science Department, Indian Institute of Information Technology, Allahabad 211012, Uttar Pradesh, India.
Singh S; Applied Science Department, Indian Institute of Information Technology, Allahabad 211012, Uttar Pradesh, India. Electronic address: sangeetasingh.iiita@gmail.com.
Mishra S; Applied Science Department, Indian Institute of Information Technology, Allahabad 211012, Uttar Pradesh, India.

Microb Pathog ; 110: 659-669, 2017 Sep.

Article em En | MEDLINE | ID: mdl-28579399

Assuntos

Acetilglucosamina/metabolismo; Adesinas Bacterianas/metabolismo; Antibacterianos/metabolismo; Biofilmes/efeitos dos fármacos; Biofilmes/crescimento & desenvolvimento; Staphylococcus aureus/efeitos dos fármacos; Staphylococcus aureus/fisiologia; Adesinas Bacterianas/química; Antibacterianos/química; Avaliação Pré-Clínica de Medicamentos; Simulação de Acoplamento Molecular; Staphylococcus aureus/metabolismo

Palavras-chave

Biofilms; Exopolysaccharide matrix; Medical devices; Poly N-acetyl glucosamine; Staphylococcus aureus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilglucosamina / Staphylococcus aureus / Biofilmes / Adesinas Bacterianas / Antibacterianos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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