FRET-based ratiometric fluorescent probe for Cu2+ with a new indolizine fluorophore.
Anal Chim Acta
; 978: 48-54, 2017 Jul 25.
Article
em En
| MEDLINE
| ID: mdl-28595726
ABSTRACT
A new fluorophore indolizine was synthesized and used as a donor to construct FRET system. The chemodosimeter shows a large Stokes shifts (193 nm), high sensitivity, and high selectivity. The probe can quickly (10 min) detect Cu2+ effectively in a wide pH range from 5 to 12 and with a detection limit as low as 9.1 × 10-9 M. Furthermore, it could be used for imaging Cu2+ in living Glioma cells which demonstrated its value of practical applications in biological systems.
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Base de dados:
MEDLINE
Assunto principal:
Cobre
/
Imagem Molecular
/
Corantes Fluorescentes
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Indolizinas
/
Ionóforos
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article