Analysis of Azithromycin Monohydrate as a Single or a Combinatorial Therapy in a Mouse Model of Severe Spinal Muscular Atrophy.

Osman, Erkan Y; Washington, Charles W; Simon, Madeline E; Megiddo, Dalia; Greif, Hagar; Lorson, Christian L

Osman, Erkan Y; Washington, Charles W; Simon, Madeline E; Megiddo, Dalia; Greif, Hagar; Lorson, Christian L.

Afiliação

Osman EY; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
Washington CW; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Simon ME; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
Megiddo D; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Greif H; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
Lorson CL; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.

J Neuromuscul Dis ; 4(3): 237-249, 2017.

Article em En | MEDLINE | ID: mdl-28598854

Assuntos

Azitromicina/farmacologia; Encéfalo/efeitos dos fármacos; Atrofia Muscular Espinal/patologia; Fármacos Neuroprotetores/farmacologia; Animais; Encéfalo/patologia; Modelos Animais de Doenças; Camundongos; Camundongos Transgênicos; Oligonucleotídeos Antissenso/farmacologia; Medula Espinal/efeitos dos fármacos; Medula Espinal/patologia

Palavras-chave

Azithromycin (AZM); Pre-mRNA splicing; Spinal muscular atrophy (SMA); Survival Motor Neuron (SMN); neurodegeneration

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Atrofia Muscular Espinal / Azitromicina / Fármacos Neuroprotetores Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google