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Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.
Worthmann, Anna; John, Clara; Rühlemann, Malte C; Baguhl, Miriam; Heinsen, Femke-Anouska; Schaltenberg, Nicola; Heine, Markus; Schlein, Christian; Evangelakos, Ioannis; Mineo, Chieko; Fischer, Markus; Dandri, Maura; Kremoser, Claus; Scheja, Ludger; Franke, Andre; Shaul, Philip W; Heeren, Joerg.
Afiliação
  • Worthmann A; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • John C; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Rühlemann MC; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Baguhl M; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Heinsen FA; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Schaltenberg N; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Heine M; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schlein C; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Evangelakos I; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Mineo C; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Fischer M; Institute of Food Chemistry, University of Hamburg, Hamburg, Germany.
  • Dandri M; Department of Internal Medicine I, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kremoser C; Phenex Pharmaceuticals AG, Heidelberg, Germany.
  • Scheja L; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Shaul PW; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Heeren J; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nat Med ; 23(7): 839-849, 2017 Jul.
Article em En | MEDLINE | ID: mdl-28604703

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Colesterol / Temperatura Baixa / Termogênese / Microbioma Gastrointestinal Tipo de estudo: Observational_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Colesterol / Temperatura Baixa / Termogênese / Microbioma Gastrointestinal Tipo de estudo: Observational_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article