Comparison of Two Phenotypic Algorithms To Detect Carbapenemase-Producing Enterobacteriaceae.
Antimicrob Agents Chemother
; 61(8)2017 08.
Article
em En
| MEDLINE
| ID: mdl-28607010
ABSTRACT
A novel algorithm designed for the screening of carbapenemase-producing Enterobacteriaceae (CPE), based on faropenem and temocillin disks, was compared to that of the Committee of the Antibiogram of the French Society of Microbiology (CA-SFM), which is based on ticarcillin-clavulanate, imipenem, and temocillin disks. The two algorithms presented comparable negative predictive values (98.6% versus 97.5%) for CPE screening among carbapenem-nonsusceptible Enterobacteriaceae However, since 46.2% (n = 49) of the CPE were correctly identified as OXA-48-like producers by the faropenem/temocillin-based algorithm, it significantly decreased the number of complementary tests needed (42.2% versus 62.6% with the CA-SFM algorithm).
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Penicilinas
/
Proteínas de Bactérias
/
Beta-Lactamases
/
Algoritmos
/
Imipenem
/
Beta-Lactamas
/
Testes de Sensibilidade a Antimicrobianos por Disco-Difusão
/
Enterobacteriáceas Resistentes a Carbapenêmicos
/
Antibacterianos
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article