Next-generation sequencing and clinical outcomes of patients with lung adenocarcinoma treated with stereotactic body radiotherapy.

Cassidy, Richard J; Zhang, Xinyan; Patel, Pretesh R; Shelton, Joseph W; Escott, Chase E; Sica, Gabriel L; Rossi, Michael R; Hill, Charles E; Steuer, Conor E; Pillai, Rathi N; Ramalingam, Suresh S; Owonikoko, Taofeek K; Behera, Madhusmita; Force, Seth D; Fernandez, Felix G; Curran, Walter J; Higgins, Kristin A

Cassidy, Richard J; Zhang, Xinyan; Patel, Pretesh R; Shelton, Joseph W; Escott, Chase E; Sica, Gabriel L; Rossi, Michael R; Hill, Charles E; Steuer, Conor E; Pillai, Rathi N; Ramalingam, Suresh S; Owonikoko, Taofeek K; Behera, Madhusmita; Force, Seth D; Fernandez, Felix G; Curran, Walter J; Higgins, Kristin A.

Afiliação

Cassidy RJ; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Zhang X; Department of Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Patel PR; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Shelton JW; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Escott CE; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Sica GL; Department of Pathology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Rossi MR; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Hill CE; Department of Pathology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Steuer CE; Department of Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Pillai RN; Department of Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Ramalingam SS; Department of Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Owonikoko TK; Department of Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Behera M; Department of Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Force SD; Department of Thoracic Surgery, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Fernandez FG; Department of Thoracic Surgery, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Curran WJ; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Higgins KA; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.

Cancer ; 123(19): 3681-3690, 2017 Oct 01.

Article em En | MEDLINE | ID: mdl-28608966

Assuntos

Adenocarcinoma/genética; Adenocarcinoma/radioterapia; Aberrações Cromossômicas; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/radioterapia; Radiocirurgia; Adenocarcinoma/mortalidade; Adenocarcinoma/patologia; Adenocarcinoma de Pulmão; Adulto; Idoso; Idoso de 80 Anos ou mais; Análise de Variância; Quinase do Linfoma Anaplásico; Feminino; Rearranjo Gênico; Genes erbB-1; Genes p53; Genes ras; Humanos; Hibridização in Situ Fluorescente; Neoplasias Pulmonares/mortalidade; Neoplasias Pulmonares/patologia; Masculino; Pessoa de Meia-Idade; Terapia de Alvo Molecular; Recidiva Local de Neoplasia; PTEN Fosfo-Hidrolase/genética; Proteínas Proto-Oncogênicas B-raf/genética; Proteínas Proto-Oncogênicas c-met/genética; Proteínas Proto-Oncogênicas c-ret/genética; Receptores Proteína Tirosina Quinases/genética; Proteína Smad4/genética; Tirosina Quinase 3 Semelhante a fms/genética

Palavras-chave

lung adenocarcinomas; lung mutations; next-generation sequencing; stereotactic body radiotherapy; targeted therapy

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Aberrações Cromossômicas / Radiocirurgia / Sequenciamento de Nucleotídeos em Larga Escala / Neoplasias Pulmonares Tipo de estudo: Guideline / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google