Hormone replacement treatment choices in complete androgen insensitivity syndrome: an audit of an adult clinic.
Endocr Connect
; 6(6): 375-379, 2017 Aug.
Article
em En
| MEDLINE
| ID: mdl-28615185
ABSTRACT
OBJECTIVE:
To review the treatment choices of women with complete androgen insensitivity syndrome (CAIS) at a single tertiary centre.DESIGN:
Retrospective review. PATIENTS Women with CAIS identified from our database.RESULTS:
The study group comprised 141 women with CAIS. Eleven percent (16/141) of women had gonads in situ, 3 of whom were under workup for gonadectomy. The age of gonadectomy in the remainder 125 women was 17 (0.1-53) years. The most common form of HRT was oral oestrogen or transdermal oestrogen in 80% (113/141). 13/141 (9%) women used vaginal oestrogens alone or together with other forms of HRT. Testosterone preparations had been used by 17% (24/141) of women and were currently used in 10% (14/141). Of those who had used testosterone, 42% (10/24) had chosen not to continue after a therapeutic trial.CONCLUSIONS:
In a clinic offering individualised multidisciplinary care for women with CAIS, we found that the majority of women chose oestrogen-based treatment while a significant minority used testosterone.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article