Multiple and complex influences of connexins and pannexins on cell death.
Biochim Biophys Acta Biomembr
; 1860(1): 182-191, 2018 Jan.
Article
em En
| MEDLINE
| ID: mdl-28625689
ABSTRACT
Cell death is a fundamental process for organogenesis, immunity and cell renewal. During the last decades a broad range of molecular tools were identified as important players for several different cell death pathways (apoptosis, pyroptosis, necrosis, autosis
). Aside from these direct regulators of cell death programs, several lines of evidence proposed connexins and pannexins as potent effectors of cell death. In the present review we discussed the potential roles played by connexins, pannexins and innexins in the different cell death programs at different scales from gap junction intercellular communication to protein-protein interactions. This article is part of a Special Issue entitled Gap Junction Proteins edited by Jean Claude Herve.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Apoptose
/
Conexinas
/
Piroptose
/
Necrose
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article