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Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity.
Zhang, Deqiang; Tong, Xin; VanDommelen, Kyle; Gupta, Neil; Stamper, Kenneth; Brady, Graham F; Meng, Zhuoxian; Lin, Jiandie; Rui, Liangyou; Omary, M Bishr; Yin, Lei.
Afiliação
  • Zhang D; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Tong X; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • VanDommelen K; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Gupta N; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Stamper K; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Brady GF; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Meng Z; Department of Pathology and Pathophysiology, Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
  • Lin J; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan Medical Center, Ann Arbor, Michigan, USA.
  • Rui L; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan Medical Center, Ann Arbor, Michigan, USA.
  • Omary MB; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Yin L; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
J Clin Invest ; 127(7): 2855-2867, 2017 Jun 30.
Article em En | MEDLINE | ID: mdl-28628040
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Carboidratos da Dieta / Doença Hepática Induzida por Substâncias e Drogas / Resposta a Proteínas não Dobradas / Frutose / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Carboidratos da Dieta / Doença Hepática Induzida por Substâncias e Drogas / Resposta a Proteínas não Dobradas / Frutose / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article