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Novel indolyl-chalcone derivatives inhibit A549 lung cancer cell growth through activating Nrf-2/HO-1 and inducing apoptosis in vitro and in vivo.
Zhao, Xuan; Dong, WenLiang; Gao, YuanDi; Shin, Dong-Shoo; Ye, Qing; Su, Le; Jiang, Fan; Zhao, BaoXiang; Miao, JunYing.
Afiliação
  • Zhao X; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan, 250100, China.
  • Dong W; Department of Chemistry, Changwon National University, Changwon, 51140, South Korea.
  • Gao Y; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan, 250100, China.
  • Shin DS; Department of Chemistry, Changwon National University, Changwon, 51140, South Korea.
  • Ye Q; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Su L; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan, 250100, China.
  • Jiang F; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Zhao B; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, China. bxzhao@sdu.edu.cn.
  • Miao J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan, 250100, China. miaojy@sdu.edu.cn.
Sci Rep ; 7(1): 3919, 2017 06 20.
Article em En | MEDLINE | ID: mdl-28634389
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalconas / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalconas / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article