CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery.

Wang, Hong-Xia; Li, Mingqiang; Lee, Ciaran M; Chakraborty, Syandan; Kim, Hae-Won; Bao, Gang; Leong, Kam W

Wang, Hong-Xia; Li, Mingqiang; Lee, Ciaran M; Chakraborty, Syandan; Kim, Hae-Won; Bao, Gang; Leong, Kam W.

Afiliação

Wang HX; Department of Biomedical Engineering, Columbia University , New York, New York 10027, United States.
Li M; Department of Biomedical Engineering, Columbia University , New York, New York 10027, United States.
Lee CM; Department of Bioengineering, Rice University , Houston, Texas 77005, United States.
Chakraborty S; Department of Biomedical Engineering, Columbia University , New York, New York 10027, United States.
Kim HW; Institute of Tissue Regeneration Engineering (ITREN) and Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University , Cheonan 31116, Korea.
Bao G; Department of Bioengineering, Rice University , Houston, Texas 77005, United States.
Leong KW; Department of Biomedical Engineering, Columbia University , New York, New York 10027, United States.

Chem Rev ; 117(15): 9874-9906, 2017 Aug 09.

Article em En | MEDLINE | ID: mdl-28640612

Assuntos

Sistemas CRISPR-Cas/genética; Edição de Genes; Técnicas de Transferência de Genes; Terapia Genética/métodos; Modelos Biológicos; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Técnicas de Transferência de Genes / Sistemas CRISPR-Cas / Edição de Genes / Modelos Biológicos Tipo de estudo: Qualitative_research Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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