The Impact of Gender on Tumour Stage in In-House Complications and Choice of Urinary Diversion: Results of the Austrian Cystectomy Registry.
Urol Int
; 99(4): 429-435, 2017.
Article
em En
| MEDLINE
| ID: mdl-28641294
ABSTRACT
INTRODUCTION AND OBJECTIVES:
Bladder cancer is characterized by gender-dependent disparities. To further address this issue, we analysed a prospective, multicentre cystectomy registry.METHODS:
An online database was developed that included patient demographics, intra/perioperative data, surgical data and in-house complications.RESULTS:
Four hundred fifty-eight patients (112 [24.5%] women and 346 [75.5%] men) were analysed. Men and women were comparable regarding age (mean 68 years), body mass index (mean 26.5) and the mean Charlson score (4.8). Women had more advanced tumour-stages (pT3/pT4; women 57.1%; men 48.1%). The rate of incontinent urinary diversion was higher in women (83.1%) than in men (60.2%) and in a multivariate analysis, the strongest predictors were M+ status (OR 11.2), female gender (OR 6.9) and age (OR 6.5). Women had a higher intraoperative blood transfusion rate. The overall rate of in-house complications was similar in both genders (men 32.0%, women 32.6%). Severe (Clavien-Dindo grade >2) medical (women 6.3%; men 5.2%) and surgical (women 21.5%; men 14.4%) in-house complications, however, were more frequent in women.CONCLUSIONS:
This multicentre registry demonstrates several gender-related differences in patients undergoing radical cystectomy. The higher transfusion rate, the rare use of orthotopic bladder substitutes and the higher in-house complication rate underline the higher complexity of this procedure in women.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
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Derivação Urinária
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Neoplasias da Bexiga Urinária
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Cistectomia
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Disparidades em Assistência à Saúde
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Tomada de Decisão Clínica
Tipo de estudo:
Clinical_trials
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Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article