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Dosimetric characterization of optically stimulated luminescence dosimeter with therapeutic photon beams for use in clinical radiotherapy measurements.
Ponmalar, Retna; Manickam, Ravikumar; Ganesh, K M; Saminathan, Sathiyan; Raman, Arun; Godson, Henry Finlay.
Afiliação
  • Ponmalar R; Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka; Department of Radiotherapy, Christian Medical College, Vellore, Tamil Nadu, India.
  • Manickam R; Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.
  • Ganesh KM; Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.
  • Saminathan S; Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.
  • Raman A; Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.
  • Godson HF; Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka; Department of Radiotherapy, Christian Medical College, Vellore, Tamil Nadu, India.
J Cancer Res Ther ; 13(2): 304-312, 2017.
Article em En | MEDLINE | ID: mdl-28643752
AIM: The modern radiotherapy techniques impose new challenges for dosimetry systems with high precision and accuracy in in vivo and in phantom dosimetric measurements. The knowledge of the basic characterization of a dosimetric system before patient dose verification is crucial. This incites the investigation of the potential use of nanoDot optically stimulated luminescence dosimeter (OSLD) for application in radiotherapy with therapeutic photon beams. MATERIALS AND METHODS: Measurements were carried out with nanoDot OSLDs to evaluate the dosimetric characteristics such as dose linearity, dependency on field size, dose rate, energy and source-to-surface distance (SSD), reproducibility, fading effect, reader stability, and signal depletion per read out with cobalt-60 (60 Co) beam, 6 and 18 MV therapeutic photon beams. The data acquired with OSLDs were validated with ionization chamber data where applicable. RESULTS: Good dose linearity was observed for doses up to 300 cGy and above which supralinear behavior. The standard uncertainty with field size observed was 1.10% ± 0.4%, 1.09% ± 0.34%, and 1.2% ± 0.26% for 6 MV, 18 MV, and 60 Co beam, respectively. The maximum difference with dose rate was 1.3% ± 0.4% for 6 MV and 1.4% ± 0.4% for 18 MV photon beams. The largest variation in SSD was 1.5% ± 1.2% for 60 Co, 1.5% ± 0.9% for 6 MV, and 1.5% ± 1.3% for 18 MV photon beams. The energy dependence of OSL response at 18 MV and 60 Co with 6 MV beam was 1.5% ± 0.7% and 1.7% ± 0.6%, respectively. In addition, good reproducibility, stability after the decay of transient signal, and predictable fading were observed. CONCLUSION: The results obtained in this study indicate the efficacy and suitability of nanoDot OSLD for dosimetric measurements in clinical radiotherapy.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radioterapia / Fótons / Relação Dose-Resposta à Radiação / Dosimetria por Luminescência Estimulada Opticamente Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radioterapia / Fótons / Relação Dose-Resposta à Radiação / Dosimetria por Luminescência Estimulada Opticamente Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article