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Prosthetic joint infection caused by Granulicatella adiacens: a case series and review of literature.
Quénard, Fanny; Seng, Piseth; Lagier, Jean-Christophe; Fenollar, Florence; Stein, Andreas.
Afiliação
  • Quénard F; Centre de Référence des Infections Ostéo-Articulaires (CRIOA) Sud-Méditerranée, Assistance Publique - Hôpitaux de Marseille, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.
  • Seng P; Centre de Référence des Infections Ostéo-Articulaires (CRIOA) Sud-Méditerranée, Assistance Publique - Hôpitaux de Marseille, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France. sengpiseth@yahoo.fr.
  • Lagier JC; Service de Maladies Infectieuses Tropicales et Infections Chroniques (MITIC), IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France. sengpiseth@yahoo.fr.
  • Fenollar F; Aix-Marseille Université, Unité de recherche sur les maladies infectieuses et tropicales émergentes (URMITE), UM63, CNRS 7278, IRD 198, INSERM 1095, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France. sengpiseth@yahoo.fr.
  • Stein A; Aix-Marseille Université, Unité de recherche sur les maladies infectieuses et tropicales émergentes (URMITE), UM63, CNRS 7278, IRD 198, INSERM 1095, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.
BMC Musculoskelet Disord ; 18(1): 276, 2017 Jun 23.
Article em En | MEDLINE | ID: mdl-28645272
BACKGROUND: Bone and joint infection involving Granulicatella adiacens is rare, and mainly involved in cases of bacteremia and infectious endocarditis. Here we report three cases of prosthetic joint infection involving G. adiacens that were successfully treated with surgery and prolonged antimicrobial treatment. We also review the two cases of prosthetic joint infection involving G. adiacens that are reported in the literature. CASE PRESENTATION: Not all five cases of prosthetic joint infection caused by G. adiacens were associated with bacteremia or infectious endocarditis. Dental care before the onset of infection was observed in two cases. The median time delay between arthroplasty implantation and the onset of infection was of 4 years (ranging between 2 and 10 years). One of our cases was identified with 16srRNA gene sequencing, one case with MALDI-TOF mass spectrometry, and one case with both techniques. Two literature cases were diagnosed by 16srRNA gene sequencing. All five cases were cured after surgery including a two-stage prosthesis exchange in three cases, a one-stage prosthesis exchange in one case, and debridement, antibiotics, irrigation, and retention of the prosthesis in one case, and prolonged antimicrobial treatment. CONCLUSION: Prosthetic joint infection involving G. adiacens is probably often dismissed due to difficult culture or misdiagnosis, in particular in the cases of polymicrobial infection. Debridement, antibiotics, irrigation, and retention of the prosthesis associated with prolonged antimicrobial treatment (≥ 8 weeks) should be considered as a treatment strategy for prosthetic joint infection involving G. adiacens.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Relacionadas à Prótese / Carnobacteriaceae / Prótese de Quadril / Prótese do Joelho Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Relacionadas à Prótese / Carnobacteriaceae / Prótese de Quadril / Prótese do Joelho Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article