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Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression.
Kar, Gozde; Kim, Jong Kyoung; Kolodziejczyk, Aleksandra A; Natarajan, Kedar Nath; Torlai Triglia, Elena; Mifsud, Borbala; Elderkin, Sarah; Marioni, John C; Pombo, Ana; Teichmann, Sarah A.
Afiliação
  • Kar G; European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Kim JK; European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Kolodziejczyk AA; Department of New Biology, DGIST, Daegu, 42988, Republic of Korea.
  • Natarajan KN; European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Torlai Triglia E; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Mifsud B; European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Elderkin S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Marioni JC; Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert Roessle Strasse, Berlin-Buch, 13125, Germany.
  • Pombo A; Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London, WC2A 3LY, UK.
  • Teichmann SA; Department of Genetics, Evolution and Environment, University College London, Gower Street, London, WC1E 6BT, UK.
Nat Commun ; 8(1): 36, 2017 06 26.
Article em En | MEDLINE | ID: mdl-28652613
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regulação da Expressão Gênica / Proteínas do Grupo Polycomb Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regulação da Expressão Gênica / Proteínas do Grupo Polycomb Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article