A succinct access to ω-hydroxylated jasmonates via olefin metathesis.
Z Naturforsch C J Biosci
; 72(7-8): 285-292, 2017 Jul 14.
Article
em En
| MEDLINE
| ID: mdl-28665793
ABSTRACT
In higher plants, jasmonates are lipid-derived signaling molecules that control many physiological processes, including responses to abiotic stress, defenses against insects and pathogens, and development. Among jasmonates, ω-oxidized compounds form an important subfamily. The biological roles of these ω-modified derivatives are not fully understood, largely due to their limited availability. Herein, a brief (two-step), simple and efficient (>80% yield), versatile, gram-scalable, and environmentally friendly synthetic route to ω-oxidized jasmonates is described. The approach utilizes olefin cross-metathesis as the key step employing inexpensive, commercially available substrates and catalysts.
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MEDLINE
Assunto principal:
Ciclopentanos
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Alcenos
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Oxilipinas
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Modelos Químicos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article