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Interconvertible geometric isomers of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors exhibit multiple binding modes.
McConkey, Glenn A; Bedingfield, Paul T P; Burrell, David R; Chambers, Nicholas C; Cunningham, Fraser; Prior, Timothy J; Fishwick, Colin W G; Boa, Andrew N.
Afiliação
  • McConkey GA; School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
  • Bedingfield PTP; School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
  • Burrell DR; School of Mathematics & Physical Sciences, Faculty of Science and Engineering, University of Hull, Hull HU6 7RX, UK.
  • Chambers NC; School of Mathematics & Physical Sciences, Faculty of Science and Engineering, University of Hull, Hull HU6 7RX, UK.
  • Cunningham F; School of Chemistry, Faculty of Mathematics and Physical Sciences, University of Leeds, Leeds LS2 9JT, UK.
  • Prior TJ; School of Mathematics & Physical Sciences, Faculty of Science and Engineering, University of Hull, Hull HU6 7RX, UK.
  • Fishwick CWG; School of Chemistry, Faculty of Mathematics and Physical Sciences, University of Leeds, Leeds LS2 9JT, UK.
  • Boa AN; School of Mathematics & Physical Sciences, Faculty of Science and Engineering, University of Hull, Hull HU6 7RX, UK. Electronic address: a.n.boa@hull.ac.uk.
Bioorg Med Chem Lett ; 27(16): 3878-3882, 2017 08 15.
Article em En | MEDLINE | ID: mdl-28669445
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Acrilatos / Oxirredutases atuantes sobre Doadores de Grupo CH-CH Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Acrilatos / Oxirredutases atuantes sobre Doadores de Grupo CH-CH Idioma: En Ano de publicação: 2017 Tipo de documento: Article