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Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
Ellermann, Manuel; Eheim, Ashley; Rahm, Fredrik; Viklund, Jenny; Guenther, Judith; Andersson, Martin; Ericsson, Ulrika; Forsblom, Rickard; Ginman, Tobias; Lindström, Johan; Silvander, Camilla; Trésaugues, Lionel; Giese, Anja; Bunse, Stefanie; Neuhaus, Roland; Weiske, Jörg; Quanz, Maria; Glasauer, Andrea; Nowak-Reppel, Katrin; Bader, Benjamin; Irlbacher, Horst; Meyer, Hanna; Queisser, Nina; Bauser, Marcus; Haegebarth, Andrea; Gorjánácz, Mátyás.
Afiliação
  • Ellermann M; Bayer AG , Berlin, Germany.
  • Eheim A; Bayer AG , Berlin, Germany.
  • Rahm F; Sprint Bioscience , Huddinge, Sweden.
  • Viklund J; Sprint Bioscience , Huddinge, Sweden.
  • Guenther J; Bayer AG , Berlin, Germany.
  • Andersson M; Sprint Bioscience , Huddinge, Sweden.
  • Ericsson U; Sprint Bioscience , Huddinge, Sweden.
  • Forsblom R; Sprint Bioscience , Huddinge, Sweden.
  • Ginman T; Sprint Bioscience , Huddinge, Sweden.
  • Lindström J; Sprint Bioscience , Huddinge, Sweden.
  • Silvander C; Sprint Bioscience , Huddinge, Sweden.
  • Trésaugues L; Sprint Bioscience , Huddinge, Sweden.
  • Giese A; Bayer AG , Berlin, Germany.
  • Bunse S; Bayer AG , Berlin, Germany.
  • Neuhaus R; Bayer AG , Berlin, Germany.
  • Weiske J; Bayer AG , Berlin, Germany.
  • Quanz M; Bayer AG , Berlin, Germany.
  • Glasauer A; Bayer AG , Berlin, Germany.
  • Nowak-Reppel K; Bayer AG , Berlin, Germany.
  • Bader B; Bayer AG , Berlin, Germany.
  • Irlbacher H; Bayer AG , Berlin, Germany.
  • Meyer H; Bayer AG , Berlin, Germany.
  • Queisser N; Bayer AG , Berlin, Germany.
  • Bauser M; Bayer AG , Berlin, Germany.
  • Haegebarth A; Bayer AG , Berlin, Germany.
  • Gorjánácz M; Bayer AG , Berlin, Germany.
ACS Chem Biol ; 12(8): 1986-1992, 2017 08 18.
Article em En | MEDLINE | ID: mdl-28679043
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morfolinas / Sistemas de Liberação de Medicamentos / Monoéster Fosfórico Hidrolases / Enzimas Reparadoras do DNA / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morfolinas / Sistemas de Liberação de Medicamentos / Monoéster Fosfórico Hidrolases / Enzimas Reparadoras do DNA / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article