Ancestral Reconstruction Approach to Acetylcholine Receptor Structure and Function.

Prinston, Jethro E; Emlaw, Johnathon R; Dextraze, Mathieu F; Tessier, Christian J G; Pérez-Areales, F Javier; McNulty, Melissa S; daCosta, Corrie J B

Prinston, Jethro E; Emlaw, Johnathon R; Dextraze, Mathieu F; Tessier, Christian J G; Pérez-Areales, F Javier; McNulty, Melissa S; daCosta, Corrie J B.

Afiliação

Prinston JE; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada.
Emlaw JR; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada.
Dextraze MF; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada.
Tessier CJG; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada.
Pérez-Areales FJ; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada.
McNulty MS; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada.
daCosta CJB; Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, 10 Marie-Curie, Ottawa, ON K1N 6N5, Canada. Electronic address: cdacosta@uottawa.ca.

Structure ; 25(8): 1295-1302.e3, 2017 08 01.

Article em En | MEDLINE | ID: mdl-28689969

Assuntos

Proteínas de Peixes/química; Receptores Colinérgicos/química; Homologia de Sequência de Aminoácidos; Acetilcolina/metabolismo; Substituição de Aminoácidos; Sítios de Ligação; Linhagem Celular; Evolução Molecular; Proteínas de Peixes/genética; Proteínas de Peixes/metabolismo; Humanos; Ligação Proteica; Receptores Colinérgicos/genética; Receptores Colinérgicos/metabolismo

Palavras-chave

acetylcholine receptor; ancestral protein reconstruction; evolutionary biochemistry; ligand-gated ion channels; patch-clamp electrophysiology

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Colinérgicos / Homologia de Sequência de Aminoácidos / Proteínas de Peixes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google