Distribution of Chlamydia trachomatis genotypes in neonatal conjunctivitis in Hungary.
J Med Microbiol
; 66(7): 915-918, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28693667
ABSTRACT
The objective of the present study was to determine the frequency and age distribution of different Chlamydia trachomatis (CT) genotypes causing ophthalmia neonatorum (ON) in Hungary. Using CT specific PCR, we tested 76 conjunctival samples from symptomatic infants up to 3 months old in the National Centre for Epidemiology, Budapest between 2008 and 2016. CT tested positive in 30 of 76 conjunctival samples (39.5â%). The sequencing of the positive samples was successful in every case but one, and resulted in 48â% dominance for genotype E (14/29), followed by 24â% for genotype G (7/29), 10â% for J (3/29), 6.9â% for K and F (2/29), and 3.4â% for H (1/29). CT must still be regarded as a common pathogen causing ON in Hungary. Routine screening and treatment of pregnant women can be recommended to prevent these conditions. Chronic ON cases can be reduced by early diagnosis. Further research is needed to explain the dominance of genotypes E and G.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Chlamydia trachomatis
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Conjuntivite de Inclusão
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Genótipo
Tipo de estudo:
Prevalence_studies
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Risk_factors_studies
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Screening_studies
Limite:
Female
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Humans
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Infant
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Male
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Newborn
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article