In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis.

Forneris, Clarissa C; Ozturk, Seyma; Gibson, Marcus I; Sorensen, Erik J; Seyedsayamdost, Mohammad R

Forneris, Clarissa C; Ozturk, Seyma; Gibson, Marcus I; Sorensen, Erik J; Seyedsayamdost, Mohammad R.

Afiliação

Forneris CC; Departments of Chemistry and Molecular Biology, Princeton University , Princeton, New Jersey 08544, United States.
Ozturk S; Departments of Chemistry and Molecular Biology, Princeton University , Princeton, New Jersey 08544, United States.
Gibson MI; Departments of Chemistry and Molecular Biology, Princeton University , Princeton, New Jersey 08544, United States.
Sorensen EJ; Departments of Chemistry and Molecular Biology, Princeton University , Princeton, New Jersey 08544, United States.
Seyedsayamdost MR; Departments of Chemistry and Molecular Biology, Princeton University , Princeton, New Jersey 08544, United States.

ACS Chem Biol ; 12(9): 2248-2253, 2017 09 15.

Article em En | MEDLINE | ID: mdl-28696669

Assuntos

Actinomycetales/enzimologia; Antibacterianos/metabolismo; Vias Biossintéticas; Sistema Enzimático do Citocromo P-450/metabolismo; Vancomicina/metabolismo; Actinomycetales/química; Actinomycetales/metabolismo; Antibacterianos/química; Halogenação; Especificidade por Substrato; Vancomicina/química

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Actinomycetales / Vancomicina / Sistema Enzimático do Citocromo P-450 / Vias Biossintéticas / Antibacterianos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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