Application of Hydrogen/Deuterium Exchange-Mass Spectrometry to Biopharmaceutical Development Requirements: Improved Sensitivity to Detection of Conformational Changes.

Bonnington, Lea; Lindner, Ingo; Gilles, Ulrich; Kailich, Tobias; Reusch, Dietmar; Bulau, Patrick

Bonnington, Lea; Lindner, Ingo; Gilles, Ulrich; Kailich, Tobias; Reusch, Dietmar; Bulau, Patrick.

Afiliação

Bonnington L; Pharma Technical Development, Roche Diagnostics GmbH , Nonnenwald 2, 82377 Penzberg, Germany.
Lindner I; Pharma Technical Development, Roche Diagnostics GmbH , Nonnenwald 2, 82377 Penzberg, Germany.
Gilles U; Pharma Technical Development, Roche Diagnostics GmbH , Nonnenwald 2, 82377 Penzberg, Germany.
Kailich T; Pharma Technical Development, Roche Diagnostics GmbH , Nonnenwald 2, 82377 Penzberg, Germany.
Reusch D; Pharma Technical Development, Roche Diagnostics GmbH , Nonnenwald 2, 82377 Penzberg, Germany.
Bulau P; Pharma Technical Development, Roche Diagnostics GmbH , Nonnenwald 2, 82377 Penzberg, Germany.

Anal Chem ; 89(16): 8233-8237, 2017 08 15.

Article em En | MEDLINE | ID: mdl-28700824

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article