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cGAS surveillance of micronuclei links genome instability to innate immunity.
Mackenzie, Karen J; Carroll, Paula; Martin, Carol-Anne; Murina, Olga; Fluteau, Adeline; Simpson, Daniel J; Olova, Nelly; Sutcliffe, Hannah; Rainger, Jacqueline K; Leitch, Andrea; Osborn, Ruby T; Wheeler, Ann P; Nowotny, Marcin; Gilbert, Nick; Chandra, Tamir; Reijns, Martin A M; Jackson, Andrew P.
Afiliação
  • Mackenzie KJ; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Carroll P; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Martin CA; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Murina O; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Fluteau A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Simpson DJ; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Olova N; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Sutcliffe H; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Rainger JK; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Leitch A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Osborn RT; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Wheeler AP; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Nowotny M; Laboratory of Protein Structure, International Institute of Molecular and Cell Biology, Warsaw, Poland.
  • Gilbert N; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Chandra T; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Reijns MAM; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Jackson AP; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
Nature ; 548(7668): 461-465, 2017 08 24.
Article em En | MEDLINE | ID: mdl-28738408
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Instabilidade Genômica / Micronúcleos com Defeito Cromossômico / Imunidade Inata / Nucleotidiltransferases Tipo de estudo: Screening_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Instabilidade Genômica / Micronúcleos com Defeito Cromossômico / Imunidade Inata / Nucleotidiltransferases Tipo de estudo: Screening_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article