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A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide-induced proarrhythmic early afterdepolarizations.
Al-Owais, Moza M; Hettiarachchi, Nishani T; Kirton, Hannah M; Hardy, Matthew E; Boyle, John P; Scragg, Jason L; Steele, Derek S; Peers, Chris.
Afiliação
  • Al-Owais MM; Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
  • Hettiarachchi NT; Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
  • Kirton HM; Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
  • Hardy ME; Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
  • Boyle JP; Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
  • Scragg JL; Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
  • Steele DS; Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
  • Peers C; Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and c.s.peers@leeds.ac.uk.
FASEB J ; 31(11): 4845-4854, 2017 11.
Article em En | MEDLINE | ID: mdl-28743763
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Monóxido de Carbono / Ácido Peroxinitroso / Miócitos Cardíacos / Canal de Potássio ERG1 / Potenciais da Membrana Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Monóxido de Carbono / Ácido Peroxinitroso / Miócitos Cardíacos / Canal de Potássio ERG1 / Potenciais da Membrana Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article