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Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens.
Sun, Cuixiang; Deng, Yonghong; Hunt, Diana K; Fyfe, Corey; Chen, Chi-Li; Clark, Roger B; Grossman, Trudy H; Sutcliffe, Joyce A; Xiao, Xiao-Yi.
Afiliação
  • Sun C; Discovery Chemistry, Tetraphase Pharmaceuticals, Inc., Watertown, MA, USA.
  • Deng Y; Discovery Chemistry, Tetraphase Pharmaceuticals, Inc., Watertown, MA, USA.
  • Hunt DK; Discovery Chemistry, Tetraphase Pharmaceuticals, Inc., Watertown, MA, USA.
  • Fyfe C; Department of Microbiology, Tetraphase Pharmaceuticals. Inc., Watertown, MA, USA.
  • Chen CL; Discovery Chemistry, Tetraphase Pharmaceuticals, Inc., Watertown, MA, USA.
  • Clark RB; Discovery Chemistry, Tetraphase Pharmaceuticals, Inc., Watertown, MA, USA.
  • Grossman TH; Department of Microbiology, Tetraphase Pharmaceuticals. Inc., Watertown, MA, USA.
  • Sutcliffe JA; Department of Microbiology, Tetraphase Pharmaceuticals. Inc., Watertown, MA, USA.
  • Xiao XY; Discovery Chemistry, Tetraphase Pharmaceuticals, Inc., Watertown, MA, USA.
J Antibiot (Tokyo) ; 71(2): 287-297, 2018 02.
Article em En | MEDLINE | ID: mdl-28743974
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetraciclinas / Bactérias Gram-Negativas / Antibacterianos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetraciclinas / Bactérias Gram-Negativas / Antibacterianos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article