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Synthesis, α-glucosidase inhibitory activity and in silico study of tris-indole hybrid scaffold with oxadiazole ring: As potential leads for the management of type-II diabetes mellitus.
Taha, Muhammad; Rahim, Fazal; Imran, Syahrul; Ismail, Nor Hadiani; Ullah, Hayat; Selvaraj, Manikandan; Javid, Muhammad Tariq; Salar, Uzma; Ali, Muhammad; Khan, Khalid Mohammed.
Afiliação
  • Taha M; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), University of Dammam, Dammam 31441, Saudi Arabia. Electronic address: taha_hej@yahoo.com.
  • Rahim F; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan.
  • Imran S; Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia.
  • Ismail NH; Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia.
  • Ullah H; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan.
  • Selvaraj M; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia.
  • Javid MT; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan.
  • Salar U; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Ali M; Department of Chemistry, COMSATS Institute of Information Technology, University Road, Abbottbad 22060, KPK, Pakistan.
  • Khan KM; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Bioorg Chem ; 74: 30-40, 2017 10.
Article em En | MEDLINE | ID: mdl-28750203
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Diabetes Mellitus Tipo 2 / Alfa-Glucosidases / Simulação de Acoplamento Molecular / Inibidores de Glicosídeo Hidrolases / Hipoglicemiantes / Indóis Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Diabetes Mellitus Tipo 2 / Alfa-Glucosidases / Simulação de Acoplamento Molecular / Inibidores de Glicosídeo Hidrolases / Hipoglicemiantes / Indóis Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article